Available online 2018-07-31, published 2018-07-31, Korean Herb. Med. Inf. 2018;22(1)

강황의 항치매효과에 대한 체계적인 문헌고찰

Analysis of Papers on Curcuma longa Rhizoma for Possibility Evaluation of Therapeutic against dementia

Abstract
Objectives
The incidence of degenerative diseases is increasing as society ages, and this increased the economic burden on
society. Oxidative stress was also under suspicion as one of the causes. Recent studies have found that Curcuma
longa Rhizoma had antioxidant, anti-inflammatory, antimutagenic, and anticancer effects. Through this study,
we figure out trends in Curcuma longa Rhizoma research and evaluate the therapeutic potential of Curcuma
longa Rhizoma for dementia.
Methods
The search was made using domestic and international internet search sites. “Naver academic,” “Google scholar,” “Korea
institute of oriental medicine (KIOM OASIS),” “Korean traditional knowledge portal (KTKP),” “Library of Congress,”
“Research information sharing service (RISS),” “National Digital Science Links (NDSL),” and “Pub med” are used to
search. The searched for words were “turmeric,” “Curcuma longa Rhizoma,” “antioxidant,” and “nerve regeneration.”
Results
It could be seen that a lot of research done on Curcuma longa recently. In previous studies, the most common
research disease was cancer. In previous studies, the most common effects of Curcuma longa was antioxidant and
anticancer. Curcumin, Vitamin B1, and various essential oils were the functional components of Curcuma longa
Rhizoma. Curcuma longa Rhizoma performs DPPH radical scavenging activity and ABTS radical cation
decolorization activity; it inhibits NO and iNOS.
Conclusion
The destruction of nerve cells due to oxidative stress is a cause of dementia. Curcuma longa Rhizoma have
antioxidant effects. Therefore, we believed that it is an effective treatment for dementia. Various studies will
be made on Curcuma longa Rhizoma.

Keyword: Curcuma longa, Rhizoma dementia, antioxidant, Korean medicine

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